Route 11/460 in the Elliston area re-opened around 2:15 a.m.
The Virginia Department of Transportation says all lanes of Route 11/460 in Montgomery County in the community of Elliston are currently closed.
An overturned tractor-trailer and downed power lines are blocking both eastbound lanes and both westbound lanes.
Since 4:30 p.m. Tuesday, Route 11/460 has been serving as the detour route for southbound Interstate 81, which is currently closed.
Drivers should consider alternate routes or expect delays on Route 11/460 and on southbound Interstate 81 in Montgomery County.
No estimated time for reopening Route 11/460 has been established at this time.